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Iris Valera-Larios on blood disorder treatments : What is the incidence of ITP? In the USA about 3,000 to 4,000 of the population have ITP at any one time, and it is not more prevalent in any particular racial or ethnic group. What are the symptoms of ITP? Some people with ITP, especially those with a count over 50, may have no symptoms at all, and their ITP only noticed during a routine blood test. Even people with very low counts, can sometimes have few symptoms.
ITP that arises suddenly is known as acute ITP, if the platelet count remains low after 3 months it will be called persistent ITP, and if the platelet count has not returned to normal after 12 months it will be called chronic ITP. The severity of the condition is determined by adding the names severe or mild. Thus, for example, someone with chronic severe ITP would have had a troublesome condition with a very low platelet count for over a year.
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What causes ITP? ITP is an autoimmune disease. In some cases, this is due to a self-reacting antibody binding to the surface of the platelets, causing both to be removed by cells in the spleen and elsewhere. However, other immune abnormalities have been found in some patients with ITP that affect lymphocytes (a type of white cell) or megakaryocytes (the precursor cells of platelets). These differences may help explain why patients vary in their response to treatment. Why some people develop this “autoimmune” process and others do not is not fully understood. In some individuals, a viral infection may act as an environmental trigger to the process and your doctors may test for triggers such as infection when you are first assessed.
The symptoms of ITP may look like other medical problems. Always consult your health care provider for a diagnosis. How is idiopathic thrombocytopenic purpura diagnosed? In addition to a complete medical history and physical exam, you may have these tests: Complete blood count (CBC). A measurement of size, number, and maturity of different blood cells in a specific volume of blood (to measure platelets. Additional blood and urine tests. These tests are done to measure bleeding time and detect possible infections, including a special blood test called an antiplatelet antibody test. Find extra details on Iris Valera Larios.
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What are the symptoms of idiopathic thrombocytopenic purpura? Normal platelet count is in the range of 150,000 to 450,000. With ITP, the platelet count is less than 100,000. By the time significant bleeding occurs, you may have a platelet count of less than 10,000. The lower the platelet count, the greater the risk of bleeding. Because platelets help stop bleeding, the symptoms of ITP are related to increased bleeding. However, each person may experience symptoms differently.